In premature infants there is no decrease in 24-hour posttransfusion allogeneic red blood cell recovery after 42 days of storage

Effect of gamma irradiation on the in vivo recovery of stored red blood cells.

Gamma irradiation of blood components is used to prevent posttransfusion graft versus host disease. This process has been demonstrated to cause an increase in the permeability of the red blood cell membrane to potassium and sodium. Because of this red cell membrane lesion, it is important to investigate the effect of irradiation on the posttransfusion recovery of stored red blood cells. In the ...

Evaluation of Blood Storage Lesions in Leuko-depleted Red Blood Cell Units

Background: Red blood cells (RBCs) undergo biochemical and morphologic alterations during storage that are known as the storage lesions causing decreased RBC quality and are correlated with transfusion reactions in certain groups especially in infants and critically ill patients. Microvesicles (MVs) as one of storage lesions may be derived from various cell types and have key roles in several...

Why is it important to assess indications for red blood cell transfusion in premature infants?

Linezolid Induced Twice Pure Red Cell Aplasia in a Patient with Central Nervous System Infection after Allogeneic Stem Cell Transplantation

Linezolid (LZD), severed as the first oxazolidinone antibiotic, was active against multidrug-resistant gram-positive strains. LZD can induce thrombocytopenia, anemia and leukocytopenia. Currently, reports on pure red cell aplasia (PRCA) cases induced by LZD are relatively rare [4-7]. In this paper, we reported a patient with PRCA twice induced by LZD. A 37-year-old man was diagnosed with myelody...

Linezolid Induced Twice Pure Red Cell Aplasia in a Patient with Central Nervous System Infection after Allogeneic Stem Cell Transplantation

Linezolid (LZD), severed as the first oxazolidinone antibiotic, was active against multidrug-resistant gram-positive strains. LZD can induce thrombocytopenia, anemia and leukocytopenia. Currently, reports on pure red cell aplasia (PRCA) cases induced by LZD are relatively rare [4-7]. In this paper, we reported a patient with PRCA twice induced by LZD. A 37-year-old man was diagnosed with myelody...